Biopharmaceutical
Biopharmaceutical
With over 60 years of experience, Astro Pak understands that corrosion, bio-burden, rouge and other surface contaminants pose a significant threat to drug production and quality control. To address these concerns, we developed proprietary chemical cleaning processes and custom designed chemical circulating pump-skids to meet FDA compliance standards required for biopharmaceutical manufacturers.
Our pre-operational cleaning processes remove surface contaminants from metal manufacturing, fabrication and installation. Our maintenance cleaning processes remove rouge, product / by-product residue and biocontamination to ensure clean, passivated and sanitized contact surfaces and product purity. Whether we deploy our expert technical crews to your plant or process parts at one of our 9 shop locations, Astro Pak can meet your stringent cleaning requirements and provide cGMP documentation with each job we perform.
Systems & Equipment
- Boilers
- Autoclaves, Lyophilizers & Sterilizers
- Chromatography Equipment
- CIP Skids / Piping / Tanks
- Clean / Pure Steam Generators & Systems
- Chilled Water
- Collection / Hold Tanks
- Disc Stack Centrifuges
- Fermentors & Bioreactors
- Homogenizer System Piping
- Media / Buffer Vessels
- Mixers
- Parts Washers
- Plant Steam
- Process Piping & Vessels
- Purified Water Systems (RO, DI, USP, WFI)
- Stainless Steel Platforms
- WFI Stills (Multi-Effect & Vapor Compression)
Project Showcase
Related Services
Derouging
Derouging removes corrosion and discoloration from stainless steel systems, ensuring product safety and extending equipment lifespan. Various types of rouge require specific chemical or mechanical treatments to restore system integrity and prevent contamination.
Electropolishing & Mechanical Polishing
Electropolishing, mechanical polishing, and electrolytic cleaning improve the cleanability, corrosion resistance, and surface condition of stainless steel systems. Our precision processes remove surface contaminants, refine finishes, and restore stainless steel surfaces to support compliance with ASME BPE and ASTM B912 standards.
Passivation
Passivation chemically treats stainless steel to remove contaminants and form a protective layer, enhancing corrosion resistance. Our Ultra Pass® process uses a citric acid blend for superior results, ensuring equipment longevity.
Sanitization & Biofilm Removal
Sanitization and biofilm removal services target bioburden challenges with advanced, multi-stage strategies. These methods effectively strip away biofilm layers, ensuring long-term system cleanliness and compliance with industry standards.
Resources
In the biotechnology and pharmaceutical industries, chromatography skids are critical to maintaining process integrity. These complex assemblies house columns, pumps, valves, piping, and numerous flow paths, all of which must …
Many pharmaceutical products require ultra-purified water as part of their makeup. This water for injection (WFI) is purified through multiple steps to achieve a level where it consists of virtually …
One of the first forms of life, bacteria are collectively essential to the continuation of life on this planet. Like all terrestrial lifeforms, they require the presence of water to …